LRRK2 and Parkinson disease: We also assayed the sensitivity of ONS cells from patients with monogenic forms of Parkinson’s disease, LRRK2 and PINK-1 mutations, in particular (percentage change at 24 hours = -0.71%, 48 hours = -6.94%, 72 hours = -7.84% 96 hours = -11.67% and 120 hours = -11.89%).