RHD and rheumatic heart disease: Our findings confirmed the reliability of non-invasiveprenatal testing to predict the fetal RhD status.This prediction can be helpful to determine thenecessity of close fetal monitoring and the need ofmore invasive procedures in isoimmunized mothers.Another positive outcome of fetal RHD predictionis preventing unnecessary anti-D immunoglobulininjection in nonisoimmunized motherswith RhD negative fetuses.