Duringthe 1980s-1990s, the LH/FSH ratio was perceivedto be the gold standard for the diagnosis of PCOS.A higher LH/FSH ratio is no longer a characteristicattribute in PCOS as there is excess production ofLH in PCOS patients, which is associated with theinconsistency in LH/FSH ratios in various studies.Of the 80 PCOS patients in this study, 18 patientspresented with LH/FSH ratios lower than 1.5, 33patients ranged from 1.5 to 2.0, and the remaining29 had LH/FSH ratios higher than 2. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.