TSH showed positivecorrelations with BMI, hsCRP, fasting glucose,fasting insulin, insulin resistance, LH/FSH ratioand prolactin (r=0.173, P<0.05, r=0.757,r=0.772, r=0.499, r=0.583, r=0.492, r=0.693, respectively and P<0.01). This evidence concerns the gene PLOD1 and Insulin resistance.