LEP and type 2 diabetes mellitus: The metabolic disorder type 2 diabetes or non-insulin-dependent diabetes mellitus is also associated with abnormal levels of lipids and lipoproteins, including cholesterol, low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), high-density lipoprotein (HDL), triglyceride (TG), as well as leptin and adiponectin6.