For this purpose, CHI3L1 mRNA level values obtained from the complete set of 98 different grade glioma samples have been divided into three categories: values that were lower than or equal to the 25th percentile were ranked as “low” CHI3L1 mRNA level, values falling between the 25th and 75th percentile range were considered as “medium” CHI3L1 mRNA level, and values that were higher than or equal to the 75th percentile were ranked as “high” CHI3L1 mRNA levels. This evidence concerns the gene CHI3L1 and central nervous system cancer.