MBP and ischemia: There was a significant reduction in the area fraction of myelin basic protein staining as well as the myelin basic protein integrity score in the ischemia-normothermia group compared to sham controls in the intragyral white matter of the 1st and 2nd parasagittal gyri and the periventricular white matter (p < 0.05, Fig. 2 and Fig. 3).