WNT3A and malignant colon neoplasm: In MGC-803 and BGC-823 gastric cancer cells, Hep-3B hepatocarcinoma cells and Caco2 colon cancer cells, the levels of H3K4 me1/2 and H3K27 me3 were decreased, and those of H3K4 me3 and H3K27 me1/2 were increased with 100 ng/ml Wnt3a treatment for 24 hours.