PPM1D and ovarian cancer: As shown in Figure 7A, Wip1 was correlated with the endogenous expression of p-ATM, pAKT, snail, but not E-cadherin To investigate the correlation of Wip1 with p-ATM, p-AKT, snail and E-cadherin in ovarian cancer tissues, we performed immunostaining using antibodies against Wip1, p-ATM, p-AKT, snail and E-cadherin in 53 high-grade serous ovarian cancer specimens.