CCDC12 and cancer: As for CCDC12, we could not observe significant differences between cancer and normal tissues in two datasets (Chinese samples: P = 0.583, CRC tissues: 2219.9 ± 147.9 RPKM, normal colon tissue: 2118.0 ± 91.1 RPKM; Japanese samples: P = 0.062, CRC tissues: 22137.9 ± 971.7 RPKM, normal colon tissue: 24648.9 ± 870.9 RPKM).