al. reported downregulation of miR-320d in colon cancer stem cells (CD133+) compared to CD133- cells in HT-29 CRC cells, which is concordant with our data implicating miR-320 in regulating CRC tumor initiating cells using in vitro clonogenic and in vivo tumor formation assays [14]. The gene discussed is PROM1; the disease is colonic neoplasm.