Mantle Cell Lymphoma International Prognostic Index (MIPI) is a widely used prognostic model which incorporates ECOG (Eastern Cooperative Oncology Group) performance status (ranging from 0-5), age, leukocyte count, lactic dehydrogenase, and tumor cell proliferation rate (Ki67 staining) to estimate prognosis. This evidence concerns the gene MKI67 and neoplasm.