Moreover in U373FO cells, a second GBM cell line infected with pSLIK-FO (Supplementary Figure S2a), the expression of three of those genes, CA9, DDIT4, NDRG1, was similarly modulated by Omomyc, whereas PGK1 could not be compared because not responsive to hypoxia in U373FO cells (Supplementary Figure S2b). The gene discussed is DDIT4; the disease is glioblastoma.