To explore the role of MIR126 in autophagy, MM cells (cell line H28) and non-malignant mesothelial cells (cell line Met5A) transfected with MIR126 and empty plasmid were stained with acridine orange (AO) or transfected with mCHERRY-EGFP-LC3B plasmid. This evidence concerns the gene MAP1LC3B and Miyoshi myopathy.