SLC5A5 and plasmacytoma: We previously proposed and experimentally validated a mathematical model describing the radial expansion and conflation of independent spherical intratumoral infectious centers in mouse plasmacytomas treated intravenously with an oncolytic VSV encoding the NIS reporter gene.2 The model was based on immunohistochemical analysis showing that virus seeds intratumoral infection that spreads outward to neighboring cells with infected cells remaining viable before becoming apoptotic.