DQB1*06:04 was associated with resistance to SSc with ATA (P = 2.95X10-5, Pc = 0.0004, OR 0.06, 95%CI 0.01–0.45) and it was known that DQB1*06:04 and protective DRB1*13:02 are in strong linkage disequilibrium [26]. Here, HLA-DRB1 is linked to systemic sclerosis.