DRB1*07:01, DRB1*15:01, DQB1*02:02, and DQB1*06:02 were protectively associated with European SSc [6], and DRB1*01:01, DRB1*04:06, DRB1*07:01, and DPB1*02:01 were with Chinese SSc [13,14]. The gene discussed is HLA-DPB1; the disease is systemic sclerosis.