DPB1*03:01 and DPB1*09:01 are associated with SSc with ATA (P = 3.42X10-5, Pc = 0.0006, OR 3.32, 95%CI 1.92–5.74; P = 7.82X10-12, Pc = 1.33X10-10, OR 4.54, 95%CI 2.94–7.01, respectively, S4 Table). This evidence concerns the gene HLA-DPB1 and systemic sclerosis.