Some of the previous retinoblastoma copy number alteration studies limited their discussion of SCNA-profiles to correlations with total genomic disruption (Mairal, van der Wal, Zhang), while other studies also provided suggestions for putative candidate genes beyond focally altered MYCN or RB1 (Chen, Herzog, Lillington, Zielinski, Gratias, Sampieri, Mol). This evidence concerns the gene MYCN and retinoblastoma.