For example, BMPR1B is highly expressed in all regions of the brain (cerebellum, hippocampus, cerebr BMP2/BMPR1A is linked to tumour progression in dedifferentiated liposarcomasal cortex and lateral ventricle) whereas BMPR1A has only moderate expression in the cerebral cortex, suggesting that BMPR1B signalling predominates in the central nervous system. The gene discussed is BMP2; the disease is neoplasm.