ABCD1 and adrenoleukodystrophy: On the one side, structural abnormalities of mitochondria in cells of X-ALD mice have been proposed to indicate impaired mitochondrial functions [68, 69], whereas on the other side it was reported that normality in size, structure and localization of mitochondria in muscle can be detected in an ABCD1-deficient mouse model for X-ALD [70].