KRT1 and Sepsis: As shown in Figure S6, overexpression of AutA and AutR in complemented strains repressed the up-regulated expression of K1 capsule and down-regulated expression of acid resistance systems in vivo, and the expression trend of K1 capsule and acid resistance systems in complemented strains in vivo was opposite to DE205B during intracellular survival and serum resistance for sepsis in vivo.