EZH2 and neoplasm: We found that EZH2 is significantly overexpressed in high-grade triple-negative breast carcinoma: 90.9 % (50/55) of triple-negative breast carcinoma showed overexpression of EZH2 with a multiplicative score of intensity and percentage >3, and 88 % (44/50) among them showed homogeneously strong overexpression in 90 ~ 100 % tumor cells with a multiplicative score of 9 (Table 2).