To test this assumption, RAW 264.7 cells were treated with 0.1, 0.25, 0.5, 0.75 and 1 μg/ml of Zn-RIF-Tf-QD, Zn-RIF and RIF 2 h after infection by M. bovis and intracellular bacterial survival was checked. The gene discussed is TF; the disease is infection.