However, because Gd-EOB-DTPA contrasting is dependent on expression of OATP1B1/3 [18], and parasitic granuloma does not necessarily show expression of OATP1B1/3, Gd-EOB-DTPA may not be useful for differentiating between metastatic tumor and parasitic granuloma. The gene discussed is SLCO1B1; the disease is metastatic neoplasm.