Other numerous platelet abnormalities have been reported in FPD/AML including impaired platelet aggregation, decreased platelet spreading, decreased activation of alphaIIb-beta3, reduced protein phosphorylation of myosin light chain [31], decreased production of 12- hydroxyeicosatetraenoic acid or one specific protein kinase C isoform (PKC-θ) [9]. Here, PRRT2 is linked to acute myeloid leukemia.