These findings were consistent with the study of Bouchard et al. [21], who conducted a multi-stage analysis for the association between DPP4 genetic polymorphism and cardiovascular disease risk factors, such as lipids, diabetes-related phenotypes, and blood pressure in European ancestry.Thus showing that rs17848915 now merged into rs17574, rs1558957 and rs7608798 of the analyzed SNPs were associated with hyperglycaemia/diabetes, triacylglycerol and LDL-cholesterol in the first stage, but were not successfully replicated in stage 2. The gene discussed is DPP4; the disease is diabetes mellitus.