ICAM1 and type 1 diabetes mellitus: Recently, studies have also found that the genotype of rs3184504 may be involved in many diseases including blood hypertension[27, 28], eosinophil number[29], myocardial infarction, type I diabetes[15], hyper-LDL cholesterolemia[16], and the high concentration of soluble ICAM-1 that can lead to subclinical atherosclerosis[30].