An abridged list contains 23 hypermethylated genes and 4 hypomethylated genes (CACNA2D4;LRTM2, ESPNL, SECTM1, PCDH8) for AA tumor samples; whereas, 29 hypermethylated genes and 1 hypomethylated gene (BRSK2) are listed for the CA tumor samples (Table 1). The gene discussed is CACNA2D4; the disease is cancer.