IL12, IL18, and IL10 (all involved in regulation of the cell-mediated immune response) and the inflammatory cytokine TNFα were all similarly induced in SLE patients and HCs subsequent to EBV-EA/D stimulation compared to PBS stimulation (Figure 6, right) and with no difference in concentrations after stimulation (Figure 6, left). The gene discussed is IL18; the disease is systemic lupus erythematosus.