IL10 and infection: Despite the fact that both subsets induced IFNγ production, only the CD8α−CD11b+ DCs isolated at the infection peak (day 7) were able to induce proliferation of Plasmodium-specific Tg CD4+ T cells and considerable amounts of IL-4 and IL-10 [82], indicating that this subset could be responsible for the switch in the balance from the proinflammatory Th1 response seen in the first few days to a more pronounced Th2 response.