CASP3 and neoplasm: A fraction of the dichloromethane extract of Protaetia brevitarsis larva (composed of at least three free fatty acids: palmitic acid, (Z)-9-octadecenoic acid, and octadecenoic acid) expresses apoptosis-inducing activity as shown by DNA laddering and caspase-3 activation in colon 26 tumor cells [51].