IL10 and infection: IL-10 is now recognised as a multifunctional cytokine produced by many immune cell types including macrophages, monocytes, dendritic cells (DCs), TH1, TH2, TH17 and regulatory T cell subsets and B cells and a feedback regulator of diverse immune responses to infections (Reviewed in Couper et al., 2008, Moore et al., 2001, Saraiva and O'Garra, 2010).