BMP2 and colonic neoplasm: We previously reported, in a study with a larger sample size, that rs3178250 (BMP2) was associated with increased risk (ORTC/CC 1.20 95 % CI 1.05, 1.38) of developing colon cancer, as well as rectal cancer (ORCC 1.63 95 % CI 1.02, 2.60) [45].