PRDM14 has been implicated in a large number of human solid tumors (Moelans et al., 2010; Nishikawa et al., 2007; Ruark et al., 2013; Steenbergen et al., 2013; Terashima et al., 2014; Zhang et al., 2013) and acute lymphoid leukemias (Dettman et al., 2011). The gene discussed is PRDM14; the disease is acute lymphoblastic leukemia.