ANXA5 and central nervous system cancer: Flow cytometry study conducted after double staining (Annexin V+/Propidium Iodide+) of rat glioma C6 cells treated for 24 h with the compounds ID 3288, ID 3833, and doxorubicin (positive control) clearly demonstrated that the compound ID 3288 dose-dependently (0.5 and 1.0 μg/mL) induced apoptosis in these cells (Figure 4).