In fact, KLF6, JUND, HBEGF, GBP1, GADD45B, GADD45A, EIF4A3, CCNL1, CADM1, BMP2, AUXD1 and the down-regulated WDR48 (tumor suppressor gene) and TEF (transcription factor) are all genes involved in tumorigenesis and tumor progression. The gene discussed is TEF; the disease is neoplasm.