Among this, breast cancer MCF7 (p53 wild-type), MCF7 p53 knockdown (KD), MDA-MB-231 (p53 mutant), and MDA-MB-468 (p53 mutant) cells exhibited strong sensitivity to InuA treatment, with the IC50 values of 2.4, 3.7, 4.1, and 0.9 μM, respectively (Figure 1). This evidence concerns the gene TP53 and breast cancer.