In adults, CD30 is also overexpressed in other malignancies, such as anaplastic large cell lymphoma (ALCL), cutaneous T-cell lymphoma (Sézary syndrome, Mycosis fungoides), diffuse large B-cell lymphoma (DLBCL) and certain autoimmune diseases. The gene discussed is TNFRSF8; the disease is primary cutaneous T-cell non-Hodgkin lymphoma.