As shown Figure 1A, the average IHC staining score of CYR61 in the GCA tumor tissue is 66.725 with a standard deviation of 62.817 while in the normal tissue is 44.879 with a standard deviation of 50.124 (p = 0.0025), indicating that expression of CYR61 in the GCA tumor tissue is significantly higher than in the normal tissue. Here, CCN1 is linked to temporal arteritis.