In tumour tissues from the BGC-823-xenografted nude mice treated with DT-13-TPT combination, the positive areas for TUNEL, cleaved caspase-3 and NM IIA were increased, while the positive areas for p-ERK1/2, EGFR and Cav-1 were reduced (Figures 6D, 6E). Here, MAPK3 is linked to neoplasm.