RGS11 and metastatic neoplasm: Using subtractive hybridization analysis of two pairs of primary lung adenocarcinoma and their metastatic tumor counterparts in lymph nodes (LNs), we found that RGS11 was highly overexpressed in lung metastatic adenocarcinoma, and its overexpression was associated with poorer prognosis, as reflected in shorter disease-free and metastasis-free survivals.