Comparing four different HNSCC cell lines by immunoblot analysis our data show that low La protein expression correlates with low Bcl2 protein expression and high cisplatin sensitivity (low IC50 values: 12+/−1.9 μM in SCC 25 and 11+/−1.9 μM in SCC 22A) (Figure 1B, Supplementary Figure S1A and S1D). This evidence concerns the gene BCL2 and head and neck squamous cell carcinoma.