Interestingly, the La protein stimulates translation of mRNAs that have structural RNA elements located within the 5′-untranslated region (5'UTR) in common, like stem-loop structures as described in Mdm2 [1], a negative regulator of tumor suppressor p53, or internal ribosomal entry sites (IRES) as described for various viral and cellular mRNAs including tumor-promoting factors such as X-linked inhibitor of apoptosis (XIAP), cyclin D1, and Laminin B1 [2, 4, 5, 10–18]. The gene discussed is XIAP; the disease is neoplasm.