NCOA3 and hepatocellular carcinoma: To determine the effects of AIB1 on sorafenib-induced HCC cell death, HepG2 cells were stably transfected with pSUPER vector (shCtrl) or AIB1-knockdown vector pSUPER-shAIB1 (shAIB1), whereas SK-Hep1 cells which express relatively less AIB1 protein were stably transfected with pCR3.1 vector (Ctrl) or AIB1-expression vector pCR3.1-AIB1 (AIB1), and then these cells were treated with sorafenib for 24 hours.