There was a trend towards improved OS in strongly PD-L1 positive adenocarcinoma (HR 0.70, 95% CI 0.45–1.07, p = 0.096) compared to squamous cell carcinoma (HR 1.03, 95% CI 0.69–1.55, p = 0.885), although this was not significant. Here, CD274 is linked to adenocarcinoma.