We found that CD105-MVD in tumor tissue (rho = −0.321, p = 0.0015, 95 % CI −.491 to −1.128) and proximal resection margins (rho = −0.220, p = 0.0324, 95 % CI −0.403 to −0.019) correlated inversely with tumor recurrence rate. The gene discussed is ENG; the disease is neoplasm.