The absence of EGFR mutations in chordomas is shared with other cancers, such as head and neck squamous cell carcinoma and colorectal and pancreatic cancers, which are known to respond to anti‐EGFR therapy to varying degrees 52, 66, 67, 68, 69, 70, 71, 72. The gene discussed is EGFR; the disease is head and neck squamous cell carcinoma.