We found that expression of sh-KLF4 in both HCC lines significantly decreased the mRNA levels (Figure 1A), and protein levels of KLF4 (Figure 1B), while expression of KLF4 in both lines significantly increased the mRNA levels (Figure 1A), and protein levels of KLF4 (Figure 1B). Here, KLF4 is linked to hepatocellular carcinoma.