RUNX2 and melanoma: However, more studies are required to confirm the regulation of TYRO3 by RUNX1, and to decipher the role of RUNX1 in melanoma cells, which is co-regulated with RUNX2 with a Pearson's Correlation of 0.31 in cutaneous melanoma (TCGA provisional, 278 samples) using CBio Portal (http://www.cbioportal.org) [43, 44].