PPARG and breast cancer: Indeed, in the Danish prospective cohort study “Diet, Cancer and Health” (DCH), variant allele carriers of the PPARG2 Pro12Ala (rs1801282) polymorphism had a 20 % increased risk of BC per 10 g of alcohol consumed per day, whereas carriage of the wild type allele was not associated with alcohol-related BC [29], thus implicating peroxisome proliferator-activated receptor gamma (PPARγ) in alcohol-related breast carcinogenesis.