Of these, 2470 were excluded because of missing values (missingness was not mutually exclusive) on socioeconomic indicators (N = 89), behavioural factors or inflammatory markers (N = 1028), unknown diabetes status (N = 10), prevalent diabetes at baseline (N = 800) or CRP levels ≥10 mg/l (N = 1626). The gene discussed is CRP; the disease is diabetes mellitus.