EPHA3 and small cell lung carcinoma: To further verify the effect of EPHA3 on SCLC chemoresistance, we subsequently transfected SCLC cells with EPHA3 shRNAs (EPHA3-1690, −1286, −2635, −2934) and NC to knockdown the expression of EPHA3, and shRNA-1690 for H69 and H69AR cells, as well as −2934 for H446, H146, and H1688 cells (Supplementary Figure S2).