On the basis of the association between Gal-1 expression and HCC progression in vivo and in vitro, and given that EMT is considered to be a striking feature of most cancers and has an important role in cancer migration and invasion, we examined the expression of epithelial and mesenchymal markers, as well as of other molecules thought to induce EMT in cancer cells. This evidence concerns the gene GAL and hepatocellular carcinoma.